The best way to care for your furry friend is to understand how their body works and to know what to look for when it comes to their health and well-being. Lymphoma in cats is a malignant cancer of the lymphatic system, which is a collection of lymphocytes (blood cells) and organs (lymph nodes, etc.). It can affect many systems in a cat's body, leading to intestinal lymphoma in cats, and is the most common cause of spinal cord tumors.

Here's what you need to know about lymphoma so you can be the most informed pet parent you can be.

Lymphoma in Cats

According to PetCure Oncology, feline lymphoma accounts for 30% of all cancer diagnosed in cats. The most common location for lymphoma is in the intestinal tract. Also known as gastrointestinal (GI) or alimentary lymphoma, intestinal lymphoma in cats can cause vomiting and diarrhea.

There are many types of lymphoma in cats, however, and a variety of factors will determine how this cancer might affect your kitty.

Close up of cheerful Indian young couple wife and husband standing in room at home holding cute cat in hands.

Causes

The onset of feline lymphoma has been linked to the feline leukemia virus (FeLV), and, to a lesser extent, feline immunodeficiency virus (FIV). Cats who are positive for feline leukemia generally develop cancer at a younger age.

These days, because many cats are housed indoors and there's widespread testing for and vaccination against FeLV, lymphoma is less common in younger cats. Cats who are negative for the virus tend to develop lymphoma at an older age. The American Journal of Epidemiology suggests that chronic exposure to cigarette smoke may also be a risk factor for lymphoma.

Types

Because the lymphatic system interacts with every system in the body, lymphoma can affect any of these systems. The main types of lymphoma include:

  • Alimentary (digestive tract, most common)
  • Mediastinal (chest)
  • Renal (kidneys)
  • Nasal (nose)
  • Spinal (spine)
  • Cutaneous (skin)
  • Multicentric (meaning multiple systems are affected, most often the spleen and liver)

Signs

Signs of lymphoma depend on which organs are affected. Here are some of the signs to look out for according to where the lymphoma is located:

  • Chest: Open-mouth breathing, coughing, loss of appetite, weight loss and regurgitation
  • Digestive tract: Vomiting, diarrhea, constipation, loss of appetite, weight loss, lethargy and bloody stool
  • Kidneys: Excessive drinking and urinating, weight loss and loss of appetite
  • Nose: Chronic nasal discharge, bloody nose, swollen nose, sneezing, loss of appetite, eye discharge and noisy breathing
  • Spine: Weakness or paralysis of the back legs
  • Skin: Itching, hair loss and bleeding skin tumors

If you notice any of these signs in your cat, immediately contact your veterinarian. They can diagnose your cat's condition and determine the best treatment.

Diagnosis

Lymphoma is diagnosed using a combination of information. If your vet suspects your cat has lymphoma, they'll ask you about your cat's history and lifestyle. They'll likely follow up with a physical examination of your cat, laboratory testing (including bloodwork, urinalysis, and testing for FeLV and FIV) and imaging studies, such as radiographs and abdominal ultrasound.

The testing your vet recommends will vary depending on the type of lymphoma they suspect. If there's a mass or swollen lymph node, for example, they may also take biopsies.

Red tabby cat in vet clinic

Treatment

Feline lymphoma treatment is aimed at inducing cancer remission and maximizing your kitty's quality of life for as long as possible. Chemotherapy is frequently an option, and working with a veterinary oncologist will help your cat get the best possible outcome. Cats usually do well with chemotherapy and don't experience the unpleasant side effects humans experience, such as hair loss and nausea.

If chemotherapy isn't an option, cats can receive palliative care, such as with prednisone. This can generally provide remission of about two to four months, explains the Cornell Feline Health Center. Sometimes, your vet will recommend radiation and/or surgery.

Prognosis

Prognosis after treatment varies depending on the type of lymphoma, whether your cat is positive for FeLV and/or FIV, and where the cancer is located. Cats who are FeLV- or FIV-positive often have a worse prognosis. Some cats can achieve cancer remission up to several years, depending on their individual situation.

With chemotherapy, many cats — somewhere between 50% and 80%, according to the Cornell Feline Health Center — can achieve temporary remission of clinical signs and maintain a good quality of life.

Pet parents should also consult their vet about nutritional requirements for cats with lymphoma.

Prevention

While there's no way to prevent lymphoma, you can take actions to lessen your cat's chances of developing it.

Keep your cat indoors

This will prevent them from having contact with cats who are FeLV- or FIV-positive.

Test for FIV and FeLV

Have your cat tested when they're a kitten if possible. If you're adding a new cat to your household, have them tested before exposing your cat to them.

Vaccinate kittens against FeLV

(There's no FIV vaccine.) If your cat goes outdoors, keep their FeLV vaccine up to date.

Keep your cat's environment free of tobacco smoke

Secondhand smoke may increase the risk of lymphoma.

Visit your vet regularly

Early detection is key. Get your cat examined twice a year and request annual bloodwork for cats 7 years and older.

Advances in medicine and better education for pet parents continue to improve the odds for pets with cancer. From early detection to reducing risk factors, you can take steps to help your favorite feline friend live their best life.

Dr. Sarah Wooten Dr. Sarah Wooten

Dr. Sarah Wooten graduated from UC Davis School of Veterinary Medicine in 2002. A member of the American Society of Veterinary Journalists, Dr. Wooten divides her professional time between small animal practice in Greeley, Colorado, public speaking on associate issues, leadership, and client communication, and writing. She enjoys camping with her family, skiing, SCUBA, and participating in triathlons.

Related articles

Male Cat Urinary Blockages: Causes, Symptoms & Treatment

While male cat urinary blockages are common, they can be life-threatening. Learn how to spot symptoms and info on prevention, treatments & stress factors.

Understanding Why My Cat's Stomach Gurgles

If you're a cat parent, you may find yourself saying, "I wonder why my cat's stomach gurgles after they eat." Read on to learn what this gurgling may mean.

How to Get Your Cat to Take a Pill

Wondering how to get your cat to take a pill? This guide provides you with tactics for how to give a cat a pill!

Cat Napping: Why Your Cat Likes to Sleep

Learn about your cat's natural sleep cycle and why it doesn't always match your own, as well as why she likes to nap at certain times of the day.

Helping Your Cat Lose Weight: Food & Exercise Tips

Obesity is a health condition that affects many cats these days. Use these easy to follow methods to help your cat lose weight and keep it off.

Feline Urinary Tract Diseases & Infections: Facts & Nutritional Tips

Learn about the warning signs, symptoms, and treatments of urinary tract disease in cats and the affect on your cat's health and well-being.

Deciding if a Natural Food is Best for Your Cat

Understand what natural cat food really means and how to pick a high quality natural cat food for your furry friend.

What Is Cat Chirping and Why Do Cats Do It?

Discover what cat chirping sounds like, why cats make that sound and what their body language when they chirp might mean.

Grain Free Cat Food: What You Need to Know

Understand what grain free cat food actually means and whether or not it is a healthy solution to feed your cat.

Do Cats Really Have Nine Lives?

Learn all about the ancient proverb of cats having nine lives, including its origins & where it came from, its meaning, and why the number nine was chosen.

Conjunctivitis in Cats: Signs, Causes and Treatment

Learn the signs, causes and treatment methods of conjunctivitis in cats, as well as if it's a risk for you to catch it from your feline friends.

Cat Diabetes: Symptoms & Treatment

Learn from a Veterinarian: Discover the underlying causes, typical symptoms and possible treatments for both type 1 and type 2 of diabetes in cats.

Brushing & Food: Keys to Maintaining Your Cat's Oral Health

Brushing your cat's teeth is just as important as brushing your own. Learn signs or oral health problems in your cat and how to avoid them.

Cat Carrier Backpacks: How to Choose the Right One

Cat Carrier Backpacks: How to Choose the Right One

Cat Parents: Bringing Your New Cat Home

Discover ten ways to care for your new cat after adoption, from preparing your home before she arrives to making her feel comfortable once she's arrived.

Signs of a Rabid Cat and What to Do If Your Pet Is Exposed

Learn important information about rabies in cats, including how it's transmitted, common signs of infection and steps for preventing infection in your cat.

Benefits of Neutering a Cat

Learn about when the best time to spay or neuter your cat is, and the health benefits that accompany the surgery.

Using Your Kid's Old Toys as Homemade Cat Toys

Learn how to turn your surplus of old children's toys into repurposed cat toys, entertaining your cat for hours and saving you money.

What Is a Cat's Primordial Pouch?

What is a cat's primordial pouch? You may be surprised to know that it's a natural part of your kitty's biological makeup! Read on to learn more.

The Importance of Drinking Water for Your Cat

Discover why water consumption is so important to your cat's overall health, and how you can encourage your cat to drink more water.