Fleas and ticks are not just a nuisance, they're also a real threat to your pet's health. Dogs and cats not treated with flea and tick medication, either in the form of a topical treatment or a flea and tick pill, can suffer everything from flea allergy dermatitis (which causes your animal to bite and scratch himself and sometimes lose his hair) to tapeworms.

Since a single female flea can produce up to 2,000 eggs in her three-week lifespan, a dog can become infested quickly. Tick bites are even more dangerous. A single tick bite can transmit Lyme disease, Rocky Mountain spotted fever, tularemia, ehrlichiosis and other diseases. Signs and symptoms of tick-borne illnesses may take anywhere from 7 to 21 or more days to appear, according to the Centers for Disease Control.

Luckily, there are many types of flea and tick medications available to stop these tiny terrors from making their home on your dog or cat. The most popular kind of effective treatment is a topical medication generally applied once a month. A newer preventive measure is a flea and tick pill. Are you curious about which of the two methods might work best for your pet? Here's a look at the pros and cons of each type of treatment.

Oral Treatments

Boxer dog rolling in the grass with a stick in mouth

Oral flea and tick medication treatments—which come as chewables or pills — are ingested by your pet, rather than applied to his body. The medicine is transmitted to adult fleas when they bite your pet. There are different active chemicals used in different flea and tick pill medications, some of which last a few days and others that last a month. The most common active chemicals in oral treatments include:

  • Lufenuron: This compound does not kill adult fleas. Instead, any larvae produced by the adults will not survive. Medications with this chemical are approved by the Federal Drug Administration (FDA) for dogs and cats. It does not kill ticks.
  • Spinosad: Spinosad only kills adult fleas, not ticks. It works by overstimulating the flea's nervous system, which causes its death. Medicines with spinosad are not recommended for dogs with epilepsy. Harvard Medical School also reports that the FDA approved a topical medication called Natroba for humans as a head lice treatment. The active chemical in Natroba? Spinosad.
  • Nitenpyram: This fast-acting insecticide kills adult fleas in as little as thirty minutes. It doesn't have long-term effect, so it shouldn't be used for continuous flea control. Instead, it might be an option if you are planning a short-term trip to an area where you expect fleas will be present, such as a boarding kennel or a dog park. It is worth noting that most vets use this to kill fleas quickly, rather than use it as a preventative solution. It is approved for use by the FDA in cats and dogs, and it also kills ticks.

Topical Treatments

Topical flea and tick medication, also called "spot on" medications, are generally applied between the pet's shoulder blades so the pet can't lick it off. Most topical medications last a month. Some topical medications not only kill fleas and ticks, they also repel them. The most common active chemicals in topical medications are:

  • Fipronil: Fipronil works by attacking the nervous system of the parasite to paralyze fleas and ticks to ultimately kill them. Fipronil spreads over the cat or dog through body oils in about a day. It releases over time — usually about a month. It is approved by the Environmental Protection Agency (EPA) for use on cats and dogs.
  • Imidacloprid: This ingredient kills fleas by disrupting the nervous system. It kills both adult and larval stage fleas that come in contact with the pet. It is approved by the EPA for use on cats and dogs.
  • Pyrethroids: You may see pyrethroids on the list of active ingredients under a few different names. It is an organic compound derived from a flower, which makes it popular among pet owners who prefer all-natural products, though there are also synthetic pyrethroids that some manufacturers prefer because they are more stable and last longer. Pyrethroids are not approved for use on cats by the EPA, and should be used with caution on small dogs, and never in households with cats as it is extremely toxic to felines. Products with pyrethroids kill fleas, ticks and mites.

Effectiveness

Some pet owners complain that flea and tick medications don't work as well as advertised, but veterinarians and flea and tick medication producers told The New York Times that when the products are used correctly, they do work. Problems crop up when pet owners make mistakes in applications or have unrealistic expectations about how the treatments work.

Veterinarian Michael Murray told The Times that since fleas reproduce so quickly, by the time you notice them on your dog they could have produced two or three generations of offspring.

"That means by the time you start treating your pet you've got this massive amount of flea biomass in your home, flea larvae and pupae," Murray says. "It can take as little as three weeks or as long as several months for that to run its course."

A study published in Veterinary Parasitology seems to back up the veterinarians and flea product makers. The ninety-day study found that topicals were 88.4 percent effective, while oral treatments were 99.9 percent effective. There were 128 dogs from five states involved in the study.

Whatever your choice in flea and tick preventative, it is important when buying any medication that you make sure that your vet has approved the medication's use in your pet and that you are purchasing it from a reputable source. It is also important to consider heartworm treatments. If your chosen flea medication doesn't protect against heartworm, make sure to talk to your vet about how to protect your pet.

If you are wondering which treatment is the best option, please consult with your veterinarian. They will ensure to get your pet on the correct treatment plan. If you need to find a veterinarian in your area, please visit our Vet finder.

Kara Murphy Kara Murphy

Kara Murphy is a freelance writer and pet parent who lives in Erie, Pa. She has a goldendoodle named Maddie.

Related articles

How the Loss of a Pet Affects Your Other Pets

Discover how your pets might be impacted by the loss of another. Learn how to recognize their signs of grieving & how to help them cope with their loss.

Understand Your Pet's Body Condition Score

Monitoring your pet’s body condition score (BCS) can help you help your pet maintain proper growth and weight for a long, healthy life.

Flea and Tick Medication: Oral vs. Topical Treatments

Learn the difference between oral vs. topical flea and tick medications so that you can decide which one might be most effective for your dog or cat.

What Cleaning Products Are Safe for Pets?

Learn which cleaning product ingredients can be hazardous for dogs & cats, which alternatives are safer and tips for using cleaning products around pets.

How Pets Help Ease the Transition to an Empty Nest

If you're struggling with the future of an empty nest as your kids go to college or move away, pets can help ease that transition.

Adopting Special Needs Pets

Learn what it's like to adopt a special needs pet and how behavioral challenges or disabilities can be overcome to give them a proper forever home.

15 Pet-Friendly Cities Ideal for a US Road Trip

Check out our list of pet-friendly U.S. cities that are excellent travel options, offering off-leash dog parks and pet-friendly restaurants & hotels.

Pet Food Sharing: Can Cats Eat Dog Food? (& Vice Versa?)

Learn whether it's safe for cats and dogs to eat each other's food, nutritional concerns to be aware of, and how to discourage this behavior.

Understanding Sustainable Pet Food: How Your Pet's Food Impacts the Environment

Concerned about your pet's environmental impact? Learn how sustainable pet food can help you care for the planet without compromising pet nutrition.

My Pet Ate a Lizard — What Should I Do?

Learn what to do if your pet eats a lizard, including whether they can be toxic and symptoms to keep an eye on when they've swallowed one.

What Nutrients Can Help a Pet’s Immune System?

Learn why nutrients like antioxidants & amino acids can help improve your pet's immune system, as well as top antioxidants to look for in pet food.

How to Take Your Dog Or Cat's Temperature

Learning how to take a dog's temperature (even how to take a cat's temperature) is clear evidence of a pet parent's commitment to their health.

Secondhand Smoke and Pets: What You Need to Know

Learn how secondhand smoke affects your pets, including signs that smoking is affecting them, and why smoking around animals is dangerous to their health.

Kennel Cough in Dogs and Cats

Learn what kennel cough is and how to spot symptoms in your dog or cat, as well as how contagious it is and possible treatment options.

Benefits of Soy in Your Pet's Food

Learn the benefits soy beans can provide in pet food, including high sources of protein, fiber and vitamins.

Adopting a Blind Dog or Cat: What You Need to Know

If you're considering adopting a blind pet, learn tips & considerations for living with a blind cat or dog and how to prepare your home for a blind pet.

What is Styptic Powder for Dogs & Cats?

Styptic Powder for Dogs & Cats: What Does it Do?

How to Become a Pet Nutritionist or Vet

Want to know how to become a vet or a pet nutritionist? Learn the basics from veterinarian Dr. Patty Khuly, including education requirements & specialties.

Importance of DHA in your Pet's Food

Learn about DHA, Docosahexaenoic Acid, a natural omega-3 fatty acid that is essential in the development of the brain and nervous system in cats & dogs.

Vet Recommended Pet Food Explained

Vet recommended. You see the words on everything from pet food to flea medication. But what does it mean and why should you pay attention?